CMIT/MIT (Methylchloroisothiazolinone/Methylisothiazolinone Mixture)

CMIT/MIT, a mixture of Chloromethylisothiazolinone (CMIT) and Methylisothiazolinone (MIT), is a widely used antimicrobial agent. This guide provides detailed insights into the chemical properties, applications, and safety considerations of this biocidal mixture, essential for professionals across various industries.

Chemicals Characteristics

Synonyms: CMIT/MIT, MCI/MI, MCIT/MIT
Chemical Formula: C4H5NOS • C4H4ClNOS
CAS Number: 55965-84-9

Molar Weight

g/mol

Melting Point

°C

Boiling Point

°C

Flash Point

°C

Density

g/mL

Forms

Colorless to pale yellow liquid

Entire form

Key Points/Overview

MCI/MI, although effective in preventing bacterial growth in cosmetics, have been linked to lung toxicity, allergic reactions, and potential neurotoxicity. This has sparked discussions about the safety of these chemicals, particularly concerning their concentration in products and exposure limits.

Uses & Benefits

  • Common in Personal Care Products: Found in shampoos, conditioners, body washes, lotions, sunscreens, makeup removers, and more, they serve as vital preservatives.
  • Industrial Significance: Also used in industrial products like paints and adhesives.
  • Benefits: These chemicals are effective even in low concentrations, contributing to product longevity and reducing formulation costs.

Safety Information

  • Organ System Toxicity: High concentrations of MIT have shown significant toxic effects in animal studies, indicating potential risks for factory workers with high exposure levels.
  • Allergies: Both MCI and MI are known contact allergens, with MIT specifically being named ‘Allergen of the Year’ in 2013. Products with both MCI and MI tend to have a higher incidence of dermal irritation.
  • Neurotoxicity Concerns: In vitro studies have raised concerns about MIT’s neurotoxic effects, although animal studies have not conclusively confirmed these effects.

This comprehensive guide on Methylchloroisothiazolinone/Methylisothiazolinone serves as a valuable resource for understanding its properties, applications, and the necessary safety measures to be followed in its usage across diverse sectors. Adhering to safety guidelines and regulations when handling Methylchloroisothiazolinone/Methylisothiazolinone is crucial to ensure safe and effective use.