Dimethyl Formamide (DMF)

Chemicals Characteristics

Synonyms: DMF, N,N-Dimethylformamide
Chemical Formula: C₃H₇NO
CAS Number: 68-12-2

Key Points/Overview

Dimethyl Formamide, known for its excellent solvency properties, is a clear liquid that plays a crucial role in various industrial applications. Its high boiling point and ability to dissolve a wide range of substances make it an ideal solvent for many chemical reactions and processes. DMF’s miscibility with water and other organic solvents adds to its versatility, allowing it to be used in diverse contexts, from pharmaceuticals to polymer and fiber production.

The chemical’s unique properties, including its polar nature and high dielectric constant, enable it to facilitate reactions that are otherwise difficult to accomplish. DMF is particularly significant in the production of acrylic fibers and plastics, where it acts as a solvent during the polymerization process. Additionally, its use in the pharmaceutical industry is notable, especially in the production of peptides and other complex organic compounds. However, its potential health hazards necessitate stringent safety measures during handling and usage.

Uses & Benefits

• Pharmaceutical Industry: Used in the production of pharmaceuticals, especially for peptide and other complex organic syntheses.
• Polymer and Fiber Production: Integral in the manufacturing of acrylic fibers and plastics.
• Chemical Processing: A preferred solvent in various chemical reactions due to its solvency and high boiling point.
• Electronics: Used in the production of electronic components due to its dielectric properties.

Safety Information

• Health Risks: Exposure to DMF can cause serious health issues, including liver damage and other toxic effects.
• Protective Measures: Proper ventilation, use of protective gloves, and eye protection are essential when handling DMF.
• Storage and Handling: Store in a cool, dry place, away from direct sunlight and sources of ignition. It should be handled in a well-ventilated area to minimize inhalation risks.
• First Aid Measures: In case of exposure, immediate medical attention is necessary, especially if inhaled or in contact with skin.